med withdrawal

Was on 20 mg amitrip at night for 18 months then 25 for a while then 30. I developed myokemia. Muscle tics/flicks/spasm and overheating. I thought this was a development of the MS as well as early menopause.   Specialist advised possibly serotonin overdose so 10 weeks ago swapped the amitrip for nortrip. Have withdrawn amitrip successfully and gone onto nortrip as well as reduced fluox down to 40 from  50mg. Success in that there no more muscle flicks and overheating. I have also came off the contraceptive pill to help with weight loss stuff.
And now - it looks like nortrtip+fluox (tricyclic + an SSRI) has contributed to the development of tachycardia. And if it hasn’t then it now can contribute to risk of future attacks.

So I am coming off the nortrip. will decrease by 5 mg a week until gone. I wonder if the MS symptoms (pins and needles, eye blurring, neuralgia, headache, dizziness) will stay controlled, increase or not be there as all along its been side effects???? Oh I so look forward to pain. NOT.

The fluox is there to manage depression I have had since age 8 or so and not picked up till 18 and not correctly dx and treated till age 29. This is my second time on this drug. To success. First time 96-98 and withdrew slowly over 6 weeks while using st Johns wart which I then tapered off for 8 months. Stayed free of drug assistance with managing depression until 2006. A friend was dying as was my brother. I agreed to taking them knowing this would be years again. I started at 20mg but 6 months in went up slowly to 50mg. I was on the fluox on its own for 3 years before amitrip was introduced to help manage MS neurological symptoms of pins and needles etc. pain.
I tried to decrease by 10 mgs 2 year ago and symptoms returned quickly so did some more research and took note of the idea that to stay on them for 2 years from the time of feeling well which was Sept 2009.
I had a successful knee operation in April 2009 and came off 4 different types of pain relief and no longer needed a cane or walking stick to hobble with. I pinned that date for the time to wait two years to see how I manage and the depression is stable
So Sep 2011 was the date for first Prozac decrease. I have managed that decrease. Apart from the tachycardia event that has thrown me completely which is being treated as an event, not a depression relapse, my mood is stable still.
I am meant to be decreasing another 10mg of fluox but decided against that while this heart stuff is looked at.

its so tiring... what causes what, what meds interact with what, what condition takes priority... tired tired tired.
And now we have to play either keep the nortrip in and risk tachycardia or take nortrip out, replace the fluox with something that helps with depression and MS, or take nortrip out and leave the fluox is and risk the return of MS pain......

I’ve started the nortrip decrease tonight. Down to 15 mg from 20mg and will do that for one week then....

Watch this space...